Sage Journals: Discover world-class research

Retricted access

Research article

First published 2008

Disease Modifying Trials in Alzheimer's Disease: Perspectives for the Future

Bruno Vellas, Nicola Coley, Sandrine Andrieu

Journal of Alzheimer’s Disease

Open access

Review article

First published 2018-6-12

Clinical Trials for Disease-Modifying Therapies in Alzheimer’s Disease: A Primer,Lessons Learned,and a Blueprint for the Future

Jeffrey Cummings, Aaron Ritter, Kate Zhong

Journal of Alzheimer’s Disease

Open access

Research article

First published 2020

Aging and efficacy of disease-modifying therapies in multiple sclerosis: a meta-analysis of clinical trials

Yinan Zhang, Natalia Gonzalez Caldito, Afsaneh Shirani [...]

Therapeutic Advances in Neurological Disorders

Open access

Research article

First published 2025-10

Safety reporting quality in multiple sclerosis clinical trials: A review of phase III clinical trials included in FDA approval of disease-modifying treatments

William Z. Lin, Jaimie J. Lee, Anibal Chertcoff [...]

Multiple Sclerosis Journal – Experimental,Translational and Clinical

Retricted access

Research article

First published 2011-2

Designing clinical trials to test disease-modifying agents: application to the treatment trials of Alzheimer’s disease

Chengjie Xiong, Gerald van Belle, J Philip Miller [...]

Clinical Trials

Open access

Review article

First published 2026

Evolution of disease modifying therapy clinical trial design and therapeutic endpoints for Parkinson's disease

Tom Foltynie, Sonia Gandhi, Camille Carroll

Journal of Parkinson’s Disease

Open access

Review article

First published 2017

Simvastatin as a Potential Disease-Modifying Therapy for Patients with Parkinson’s Disease: Rationale for Clinical Trial,and Current Progress

Camille B. Carroll, Richard K.H. Wyse

Journal of Parkinson’s Disease

Open access

Research article

First published 2023

Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative

Cristina Gonzalez-Robles, Rimona S. Weil, Daniel van Wamelen [...]

Journal of Parkinson’s Disease

Retricted access

Research article

First published 2025-2

DISCOntinuation of disease-modifying therapies in MS: The DISCOMS extension trial

John R Corboy, Robert J Fox, Gary Cutter [...]

Multiple Sclerosis Journal

Open access

Research article

First published 2024-09-03

Modeling of Parkinson’s Disease Progression and Implications for Detection of Disease Modification in Treatment Trials

Benjamin Ribba, Tanya Simuni, Kenneth Marek [...]

Journal of Parkinson’s Disease

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