Sage Journals: Discover world-class research

Retricted access

Research article

First published 2017-7

Breakthrough Therapy Designation

Ryan Conrad, Kimberly Taylor, Miranda Raggio [...]

Therapeutic Innovation & Regulatory Science

Retricted access

Other

First published 2015-3

Breakthrough Therapy Designation

Arpita Shah

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2025

The Impact of Breakthrough Therapy Designation on Drug Safety

Hanu Tyagi, Rachna Shah

Production and Operations Management

Free access

Research article

First published 2016-3

Fludarabine add-on therapy in interferon-beta-treated patients with multiple sclerosis experiencing breakthrough disease

Steven J. Greenberg, Robert Zivadinov, Peterkin Lee-Kwen [...]

Therapeutic Advances in Neurological Disorders

Retricted access

Review article

First published 2015-10

Obinutuzumab for chronic lymphocytic leukemia: promise of the first treatment approved with breakthrough therapy designation

Ashish Kumar Kakkar, Sadasivam Balakrishnan

Journal of Oncology Pharmacy Practice

Retricted access

Research article

First published 2017-1

The Current Status of Sakigake Designation in Japan,PRIME in the European Union,and Breakthrough Therapy Designation in the United States

Hideyuki Kondo, Toshiyuki Hata, Konomi Ito [...]

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2019

Breakthrough Therapy,PRIME and Sakigake: A Comparison Between Neuroscience and Oncology in Obtaining Preferred Regulatory Status

Elena Tomaselli Muensterman, Yijia Luo, Jonathon M. Parker

Therapeutic Innovation & Regulatory Science

Retricted access

Research article

First published 2022-11

Breakthrough SARS-CoV-2 infections in MS patients on disease-modifying therapies

Irene Schiavetti, Cinzia Cordioli, Maria Laura Stromillo [...]

Multiple Sclerosis Journal

Open access

Case report

First published 2011

Three Patients with Viral Breakthrough during Pegylated Interferon Alpha-2b and Ribavirin Therapy: A Case Series

Daigo Kon, Takashi Goto, Kouichi Miura [...]

Therapeutic Advances in Gastrointestinal Endoscopy

Free access

Case report

First published 2013-7

Significant Interaction between Activated Charcoal and Antiretroviral Therapy Leading to Subtherapeutic Drug Concentrations,Virological Breakthrough and Development of Resistance

Alice L Tseng, Charles la Porte, Irving E Salit

Antiviral Therapy

Search results