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Research article

First published 2016-4

Fallacies of last observation carried forward analyses

John M Lachin

Clinical Trials

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Research article

First published 2020-6

Missing outcome data management in acute stroke trials testing iv thrombolytics. Is there risk of bias?

Jose Fernandez-Ferro, Lee H Schwamm, Miguel A Descalzo [...]

European Stroke Journal

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Other

First published 2001-10

Type I Error Rates from Mixed Effects Model Repeated Measures versus Fixed Effects Anova with Missing Values Imputed via Last Observation Carried Forward

Craig H. Mallinckrodt, W. Scott Clark, Stacy R. David

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2024

Effect of randomized treatment withdrawal of budesonide oral suspension on clinically relevant efficacy outcomes in patients with eosinophilic esophagitis: a post hoc analysis

Evan S. Dellon, Margaret H. Collins, David A. Katzka [...]

Therapeutic Advances in Gastroenterology

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Research article

First published 2014-11

Current Practice in Japan for the Prevention and Treatment of Missing Data in Confirmatory Clinical Trials

Shiro Tanaka, Satoru Fukinbara, Satoru Tsuchiya [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2004-12

The effect of correlation structure on treatment contrasts estimated from incomplete clinical trial data with likelihood-based repeated measures compared with last observation carried forward ANOVA

Craig H Mallinckrodt, Christopher J Kaiser, John G Watkin [...]

Clinical Trials

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Research article

First published 2002-2

The Case of the Missing Data: Methods of Dealing with Dropouts and other Research Vagaries

Da vid L Streiner

The Canadian Journal of Psychiatry

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Research article

First published 1991-7

The Application of the Principle of Intention–to–Treat to the Analysis of Clinical Trials

Dennis Gillings, Gary Koch

Therapeutic Innovation & Regulatory Science

Open access

Research article

First published 2025-12

Modeling the effect of longitudinal markers on left-truncated time-to-event outcomes in twin studies

Annah Muli, Mar Rodriguez-Girondo, Jeanine Houwing-Duistermaat

Statistical Methods in Medical Research

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Research article

First published 2016-6

The effect of desvenlafaxine on cognitive functioning in employed outpatients with major depressive disorder: a substudy of a randomized,double-blind,placebo-controlled trial

Sujana Reddy, Rana Fayyad, Chris J Edgar [...]

Journal of Psychopharmacology

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