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Retricted access

Research article

First published 2025-2

Absence of hippocampal pathology persists in the Q175DN mouse model of Huntington's disease despite elevated HTT aggregation

Melissa A Solem, Ross G Pelzel, Nicholas B Rozema [...]

Journal of Huntington's Disease

Open access

Review article

First published 2017

Is Huntingtin Dispensable in the Adult Brain?

Jeh-Ping Liu, Scott O. Zeitlin

Journal of Huntington's Disease

Retricted access

Research article

First published

Is There Convincing Evidence that Intermediate Repeats in the HTT Gene Cause Huntington’s Disease?

Mayke Oosterloo, Martine J. Van Belzen, Emilia K. Bijlsma [...]

Journal of Huntington's Disease

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Research article

First published 2016

Cellular Analysis of Silencing the Huntington’s Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice

Allison M. Keeler, Ellen Sapp, Kathryn Chase [...]

Journal of Huntington's Disease

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Research article

First published 2014-8

Huntingtin Supplies a csaA-Independent Function Essential for EDTA-Resistant Homotypic Cell Adhesion in Dictyostelium discoideum

Morgan N. Thompson, Marcy E. MacDonald, James F. Gusella [...]

Journal of Huntington's Disease

Open access

Review article

First published 2022

Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease

Manuel Seefelder, Fabrice A.C. Klein, Bernhard Landwehrmeyer [...]

Journal of Huntington's Disease

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Research article

First published 2020

Rab8 Promotes Mutant HTT Aggregation,Reduces Neurodegeneration,and Ameliorates Behavioural Alterations in a Drosophila Model of Huntington’s Disease

Laura Delfino, Robert P. Mason, Charalambos P. Kyriacou [...]

Journal of Huntington's Disease

Open access

Research article

First published 2024

Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions

Morgane Louessard, Michel Cailleret, Margot Jarrige [...]

Journal of Huntington's Disease

Open access

Research article

First published 2025-08

Intrastriatal Delivery of a Zinc Finger Protein Targeting the Mutant HTT Gene Allele Obviates Lipid Phenotypes in Brain and Plasma in Huntington's Disease Mice

Andrew Iwanowicz, Adel Boudi, Connor Seeley [...]

Human Gene Therapy

Open access

Review article

First published 2021-06-09

Taming the Huntington’s Disease Proteome: What Have We Learned?

Connor Seeley, Kimberly B. Kegel-Gleason

Journal of Huntington's Disease

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