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Retricted access

Research article

First published 2024-10

DPD deficiency in an Irish oncology centre: Prevalence and clinical implications

Ruth Kieran, Taylor Mitchell, Afrah Al Fazari [...]

Journal of Oncology Pharmacy Practice

Open access

Research article

First published 2023

Renal impairment and abnormal liver function tests in pre-therapeutic phenotype-based DPD deficiency screening using uracilemia: a comprehensive population-based study in 1138 patients

Sidonie Callon, Mathias Brugel, Damien Botsen [...]

Therapeutic Advances in Medical Oncology

Free access

Letter

First published 2016-1

Acquired factor VII deficiency following FOLFOX in a patient with colorectal cancer who was also DPD deficient

Muhammad Wasif Saif, Komal Wasif, Harriette Butler-Bowen [...]

Therapeutic Advances in Gastroenterology

Open access

Research article

First published 2020-7

Comparison of 4 Screening Methods for Detecting Fluoropyrimidine Toxicity Risk: Identification of the Most Effective,Cost-Efficient Method to Save Lives

Olivier Capitain, Valérie Seegers, Jean-Philippe Metges [...]

Dose-Response

Open access

Research article

First published 2023-1

Potential added value of combined DPYD/DPD genotyping and phenotyping to prevent severe toxicity in patients with a DPYD variant and decreased dihydropyrimidine dehydrogenase enzyme activity

Charlotte W Ockeloen, Aron Raaijmakers, Manon Hijmans-van der Vegt [...]

Journal of Oncology Pharmacy Practice

Open access

Research article

First published 2017-6

Letter regarding Zhao et al. entitled “ DPYD gene polymorphisms are associated with risk and chemotherapy prognosis in pediatric patients with acute lymphoblastic leukemia”

Maarten J Deenen, Linda M Henricks, Gabe S Sonke [...]

Tumor Biology

Free access

Review article

First published 2003-01

Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

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Case report

First published 2022-4

5-Fluorouracil Neurotoxicity in the Absence of Dihydropyrimidine Dehydrogenase Deficiency Case Report

Rebecca Jules, Arushi Thaper, Ryan Foster [...]

The Neurohospitalist

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Research article

First published 1995-01

Human Polymorphism in Drug Metabolism: Mutation in the Dihydropyrimidine Dehydrogenase Gene Results in Exon Skipping and Thymine Uracilurea

R. Meinsma, P. Fernandez-Salguero, A.B.P. van Kuilenburg [...]

DNA and Cell Biology

Free access

Research article

First published 2010-8

The Value of Dihydrouracil/Uracil Plasma Ratios in Predicting 5-Fluorouracil-Related Toxicity in Colorectal Cancer Patients

MH Kristensen, P Pedersen, J Mejer

Journal of International Medical Research

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