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Retricted access

Research article

First published 2026-4

Preferential Encapsulation of DNA Impurities Derived from pAAV Plasmid Backbone into Recombinant Adeno-Associated Virus Capsids

Yuzhe Yuan, Kiyoko Higashiyama, Emi Ito-Kudo [...]

Human Gene Therapy

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Research article

First published 2025-05

Encapsulation of a Single-Stranded Form of DNA Impurities into the Capsid of a Recombinant Adeno-Associated Virus

Kazuhisa Uchida, Emi Ito-Kudo, Kiyoko Higashiyama [...]

Human Gene Therapy

Open access

Research article

First published 2023-06

Quantitation of Residual Host Cell DNA in Recombinant Adeno-Associated Virus Using Droplet Digital Polymerase Chain Reaction

Kiyoko Higashiyama, Yuzhe Yuan, Noriko Hashiba [...]

Human Gene Therapy

Open access

Research article

First published 2022-01

Development and Application of a Liquid Chromatography-Mass Spectrometry Method for Residual Iodixanol Quantification in AAV-Based Gene Therapy Product Development

Yi Pu, Russell Katz, Yunqiu Chen [...]

Human Gene Therapy

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In brief

First published 1987-11

Suppression of Luminescence Background in Raman Spectroscopy by Means of Transient Optical Depletion of Causal Impurity Molecules

H. Hamaguchi, T. Tahara, M. Tasumi

Applied Spectroscopy

Open access

Research article

First published 2013-09

Pre-PCR Processing in Bioterrorism Preparedness: Improved Diagnostic Capabilities for Laboratory Response Networks

Johannes Hedman, Rickard Knutsson, Ricky Ansell [...]

Health Security

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Research article

First published 1990-9

A New Approach to the Study of Human Solid Tumor Cells by Means of FT-IR Microspectroscopy

Enzo Benedetti, Laura Teodori, Maria Luisa Trinca [...]

Applied Spectroscopy

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Research article

First published 2016-08

Optimizing a Method for the Quantification by Quantitative Real-Time Polymerase Chain Reaction of Host Cell DNA in Plasmid Vector Batches Used in Human Gene Therapy

Serge Ferro, Isabelle Fabre, Xavier Chenivesse

Human Gene Therapy Methods (Part B)

Open access

Research article

First published 2023-04

Application of Size Exclusion Chromatography with Multiangle Light Scattering in the Analytical Development of a Preclinical Stage Gene Therapy Program

Bryan Troxell, I-Wei Tsai, Kinjal Shah [...]

Human Gene Therapy

Free access

Research article

First published 2006-1

Final Amended Report on the Safety Assessment of Oxyquinoline and Oxyquinoline Sulfate as Used in Cosmetics1

International Journal of Toxicology

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