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Research article

First published 2000-12

Fluoroquinolones Inhibit Preferentially Streptococcus pneumoniae DNA Topoisomerase IV Than DNA Gyrase Native Proteins

Esteban FERNÁNDEZ-MOREIRA, Delia Balas, Irene GONZÁLEZ [...]

Microbial Drug Resistance

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Research article

First published 1999-12

Triple Helix Formation Inhibits DNA Gyrase Activity

H. Simon, I. Förtsch, G. Burckhardt [...]

Nucleic Acid Therapeutics

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Research article

First published 2021-12

Interaction of Quinolones Carrying New R1 Group with Mycobacterium leprae DNA Gyrase

Jong-Hoon Park, Tomoyuki Yamaguchi, Yuki Ouchi [...]

Microbial Drug Resistance

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Research article

First published 2007-09

A High-Throughput,Homogeneous,Bioluminescent Assay for Pseudomonas aeruginosa Gyrase Inhibitors and Other DNA-Damaging Agents

Donald T. Moir, Ming Di, Timothy Opperman [...]

Journal of Biomolecular Screening

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Research article

First published 2010-06

DNA Gyrase and Topoisomerase IV Mutations in an In Vitro Fluoroquinolone-Resistant Coxiella burnetii Strain

Iosif Vranakis, Vassilios Sandalakis, Dimosthenis Chochlakis [...]

Microbial Drug Resistance

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Research article

First published 2023-12

The Impact of Substitutions at Positions 1 and 8 of Fluoroquinolones on the Activity Against Mutant DNA Gyrases of Salmonella Typhimurium

Pondpan Suwanthada, Siriporn Kongsoi, Nami Miura [...]

Microbial Drug Resistance

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Research article

First published 2021-10

Amino Acid Substitution Ser83Ile in GyrA of DNA Gyrases Confers High-Level Quinolone Resistance to Nontyphoidal Salmonella Without Loss of Supercoiling Activity

Kentaro Koide, Lai Lai San, Ruttana Pachanon [...]

Microbial Drug Resistance

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Research article

First published 2015-2

Assays,Surrogates,and Alternative Technologies for a TB Lead Identification Program Targeting DNA Gyrase ATPase

Vaishali Humnabadkar, Prashanti Madhavapeddi, Halesha Basavarajappa [...]

Journal of Biomolecular Screening

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Research article

First published 2021-10

Effectiveness of Fluoroquinolones with Difluoropyridine Derivatives as R1 Groups on the Salmonella DNA Gyrase in the Presence and Absence of Plasmid-Encoded Quinolone Resistance Protein QnrB19

Ruttana Pachanon, Kentaro Koide, Siriporn Kongsoi [...]

Microbial Drug Resistance

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Research article

First published 2013-10

Distinguishing On-Target versus Off-Target Activity in Early Antibacterial Drug Discovery Using a Macromolecular Synthesis Assay

Mark L. Cunningham, Bryan P. Kwan, Kirk J. Nelson [...]

Journal of Biomolecular Screening

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