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Research article

First published 1999-3

Myotonic Dystrophy Protein Kinase Expressed in Rat Cardiac Muscle Is Associated with Sarcoplasmic Reticulum and Gap Junctions

Isabella Mussini, Donatella Biral, Oriano Marin [...]

Journal of Histochemistry & Cytochemistry

Open access

Review article

First published 2023-04

Drug Metabolism and Pharmacokinetics of Antisense Oligonucleotide Therapeutics: Typical Profiles,Evaluation Approaches,and Points to Consider Compared with Small Molecule Drugs

Hideo Takakusa, Norihiko Iwazaki, Makiya Nishikawa [...]

Nucleic Acid Therapeutics

Open access

Research article

First published 2007

Lead Optimization in Discovery Drug Metabolism and Pharmacokinetics/Case study: The Hepatitis C Virus (HCV) Protease Inhibitor SCH 503034

K.-C. Cheng, Walter A. Korfmacher, Ronald E. White [...]

Perspectives in Medicinal Chemistry

Retricted access

Research article

First published 2022-08

Enhanced Delivery of Ligand-Conjugated Antisense Oligonucleotides (C16-HA-ASO) Targeting Dystrophia Myotonica Protein Kinase Transcripts for the Treatment of Myotonic Dystrophy Type 1

Siham Ait Benichou, Dominic Jauvin, Thiéry De Serres-Bérard [...]

Human Gene Therapy

Open access

Research article

First published 2026-4

Identification of Kir2.1 Inhibitors from a High-Throughput Screen

Jacob L. Bouchard, Pedro de Andrade Horn, Yu Nishio [...]

ASSAY and Drug Development Technologies

Retricted access

Research article

First published 2023-3

Curing and thermal comparative study of rosin epoxy thermosets with bio-based imidoamines and commercial curing agents

Tamanna Thakur, Bharti Gaur

Journal of Elastomers & Plastics

Open access

Research article

First published 2020-05

A Fully Integrated Assay Panel for Early Drug Metabolism and Pharmacokinetics Profiling

Johan Wernevik, Fredrik Bergström, Anna Novén [...]

ASSAY and Drug Development Technologies

Retricted access

Research article

First published 2009-9

De-Risking Drug Discovery with ADDME — A voiding D rug D evelopment M istakes E arly

Katya Tsaioun, Mary Jacewicz

Alternatives to Laboratory Animals

Retricted access

Research article

First published 2009-10

New Analysis Method of Myotonic Dystrophy 1 Based on Quantitative Fluorescent Polymerase Chain Reaction

Marzena Skrzypczak-Zielinska, Anna Sulek-Piatkowska

Genetic Testing and Molecular Biomarkers

Retricted access

Research article

First published 2013-04

Systemic Delivery of a Peptide-Linked Morpholino Oligonucleotide Neutralizes Mutant RNA Toxicity in a Mouse Model of Myotonic Dystrophy

Andrew J. Leger, Leocadia M. Mosquea, Nicholas P. Clayton [...]

Nucleic Acid Therapeutics

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