Sage Journals: Discover world-class research

Retricted access

Review article

First published 2011-11

Clinically Important Effects in New Drug Development

Kanae Togo, Nobushige Matsuoka, Satoshi Hashigaki [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2019-11

Comparative Effectiveness of Cartilage Repair With Respect to the Minimal Clinically Important Difference

Kristofer J. Jones, Benjamin V. Kelley, Armin Arshi [...]

The American Journal of Sports Medicine

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Research article

First published 2023-10

Using the Delphi process to determine the minimum clinically important effect size for the Balanced-2 randomised controlled trial

Carolyn Deng, David Sidebotham

Clinical Trials

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Other

First published 2003-1

Practical Guidelines for Assessing the Clinical Significance of Health-Related Quality of Life Changes within Clinical Trials

Jeff Sloan, Tara Symonds, Delfino Vargas-Chanes [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 2005-04

Physician Attitudes Regarding Cardiovascular Risk Reduction: The Gaps Between Clinical Importance,Knowledge,and Effectiveness

John Castaldo, Jane Nester, Tom Wasser [...]

Population Health Management

Open access

Review article

First published 2022-4

Effectiveness of Platelet-Rich Plasma for Lateral Epicondylitis: A Systematic Review and Meta-analysis Based on Achievement of Minimal Clinically Important Difference

Pawel Niemiec, Karol Szyluk, Alicja Jarosz [...]

Orthopaedic Journal of Sports Medicine

Free access

Research article

First published 2024-1

Effect of Patient Characteristics on the Minimal Clinically Important Difference and Patient Acceptable Symptom State Thresholds After Arthroscopic Bankart Repair

Ignacio Pasqualini, Ignacio Tanoira, Eoghan T. Hurley [...]

The American Journal of Sports Medicine

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Research article

First published 2026

Alternative clinical trial designs to find a clinically important effect size of blood pressure-lowering on cognitive impairment and dementia

Deborah A. Levine, Rodney A. Hayward, Jeremy B. Sussman [...]

Journal of Alzheimer’s Disease

Open access

Research article

First published 2025-3

Preoperative Disability Influences Effectiveness of Minimal Clinically Important Difference and Patient Acceptable Symptom State in Predicting Patient Improvement Following Cervical Spine Surgery

Pratyush Shahi, Omri Maayan, Tejas Subramanian [...]

Global Spine Journal

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Letter

First published 1996-1

Comparison between Interleukin-2 and Interleukin-12: Effects on Monocyte Functions and Their Possible Importance in the Clinical Significance of Neopterin

P. Lissoni, S. Pittalis, M.G. Roselli [...]

The International Journal of Biological Markers

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