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Research article

First published 2025-2

In silico study of selected alkaloids as dual inhibitors of β- and γ-secretases for Alzheimer's disease

Isreal Ayobami Onifade, Haruna Isiyaku Umar, Abdullahi Tunde Aborode [...]

Journal of Alzheimer’s Disease

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Research article

First published 2013-8

Antiproliferative effects of γ-secretase inhibitor,a Notch signalling inhibitor,in multiple myeloma cells and its molecular mechanism of action

Jiasheng Hu, Xiongpeng Zhu, Quanyi Lu

Journal of International Medical Research

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Brief report

First published 2010-10-1

Are γ-secretase inhibitors detrimental for Alzheimer's disease patients?

Joel S. Ross, Bruno P. Imbimbo

Journal of Alzheimer’s Disease

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Research article

First published

γ-Secretase Modulators and Inhibitors Induce Different Conformational Changes of Presenilin 1 Revealed by FLIM and FRET

Xin Wang, Jin Cui, Wei Li [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-9-2

Acute Effect on the Aβ Isoform Pattern in CSF in Response to γ-Secretase Modulator and Inhibitor Treatment in Dogs

Erik Portelius, Bianca Van Broeck, Ulf Andreasson [...]

Journal of Alzheimer’s Disease

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Research article

First published 2011-2

Reduction of β-Amyloid Deposits by γ-Secretase Inhibitor is Associated with the Attenuation of Secondary Damage in the Ipsilateral Thalamus and Sensory Functional Improvement after Focal Cortical Infarction in Hypertensive Rats

Yusheng Zhang, Shihui Xing, Jian Zhang [...]

Journal of Cerebral Blood Flow & Metabolism

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Research article

First published 2014-7-16

Acetylcholinesterase Modulates Presenilin-1 Levels and γ-Secretase Activity

Maria-Letizia Campanari, María-Salud García-Ayllón, Olivia Belbin [...]

Journal of Alzheimer’s Disease

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Research article

First published 2013-02

γ-Secretase Inhibitors Prevent Overgrowth of Transplanted Neural Progenitors Derived from Human-Induced Pluripotent Stem Cells

Aya Ogura, Asuka Morizane, Yusuke Nakajima [...]

Stem Cells and Development

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Research article

First published 2012-2-20

A Canine Model to Evaluate Efficacy and Safety of γ-Secretase Inhibitors and Modulators

Herman Borghys, Marianne Tuefferd, Bianca Van Broeck [...]

Journal of Alzheimer’s Disease

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Research article

First published 2010-8

Inhibition of Notch Signaling Blocks Growth of Glioblastoma Cell Lines and Tumor Neurospheres

Jie Chen, Santosh Kesari, Christine Rooney [...]

Genes & Cancer

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