The study sample came from the Health and Retirement Study in 2014 and 2016. Inflammation level was assessed with C-reactive protein. Neighborhood disorder and health behaviors were self-reported. Structural equation modeling was conducted to test the objectives.

Results

Findings revealed significant direct effects of neighborhood disorder on inflammation (B = 0.034, 95% CI: 0.009, 0.058) and indirect effects via physical activity (B = 0.010, 95% CI: 0.006, 0.014). Neighborhood disorder was linked to inflammation through physical activity among older White adults, but not among older Black and Hispanic adults.

Discussion

Interventions to provide opportunities for physical activity may reduce inflammation levels among older adults living in neighborhoods with disorders. Future research may consider unique social experiences influencing inflammation among older Black and Hispanic adults.

2c:T453,

Racial discrimination against Chinese immigrants to various countries worldwide has risen sharply during the COVID-19 pandemic, but limited research exists regarding the pathways through which racial discrimination impacts older immigrants’ mental health. This study explored the relationship of perceived discrimination to depression among older Chinese immigrants living in Aotearoa New Zealand, through pathways of chronic health conditions, language barriers, and COVID-19 risks while taking into account the effects of anxiety and loneliness. Descriptive and regression analysis was conducted from a convenience sample of 1159 older Chinese immigrants aged between 55 and 80. While there was no significant direct effect of perceived discrimination to depression, the results showed a significant indirect effect of perceived discrimination, chronic illnesses, COVID-19 risks, and language barriers on depression, which was mediated by anxiety and loneliness. Ageing policies and interventions must address anti-racism to reduce the social and health inequalities faced by older ethnic people.

2d:T50a, Objectives

United States (U.S.) immigrants are rapidly aging, although little is known on how acculturation influences their disability risk.

Methods

We pooled 2000–2018 data (n = 50,075) from the National Health Interview Survey (NHIS) to examine odds of activities of daily living (ADL) disability among middle aged (40–64) and older (65+) immigrants based on three acculturation indicators while accounting for various measures.

Results

Among middle aged immigrants, citizenship was associated with higher odds of ADL disability after accounting for socioeconomic factors. Among both middle aged and older immigrants, English proficiency was associated with lower odds of ADL disability until accounting for socioeconomic factors. Among older immigrants, lower ADL disability odds were observed among those with English proficiency and greater U.S. duration.

Discussion

Acculturation had heterogenous influences on ADL disability risk among aging U.S. immigrants, while the interplay of these mechanisms shaped varied outcomes.

2e:T512, Objective

Our study examines racial/ethnic differences in loneliness and social isolation among older adults with hearing loss.

Methods

Data were drawn from the 2022 Health and Retirement Study, including participants ages ≥50 with objectively determined hearing loss (N = 1817). Linear models were employed to analyze the association between race/ethnicity and both loneliness and social isolation.

Results

Initially, Black adults reported higher loneliness scores than White adults, but this trend reversed after controlling for contextual