GEN Biotechnology - Volume 3, Number 1

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Editorial
Restricted accessEditorialFirst published February, 2024pp. 1-2
The Next Emergence of Synthetic Biology
Hana El-Samad
Research article
Restricted accessResearch articleFirst published February, 2024pp. 3-3
Call for Special Issue Papers: Diversity,Equity,and Inclusion in Biotechnology
Brian AguadoKarmella HaynesAna Maria Porras
News
Restricted accessNewsFirst published February, 2024pp. 4-9
Scenes from the J.P. Morgan Healthcare Conference 2024
Jonathan D. GrinsteinAlex Philippidis
News
Restricted accessNewsFirst published February, 2024pp. 10-14
The Versatility and Precision of DNA Origami
Sachin Rawat
Research article
Restricted accessResearch articleFirst published February, 2024pp. 15-18
On Your Marks: An Interview with Peter Marks
Peter MarksAlex PhilippidisJonathan D. Grinstein
Research article
Restricted accessResearch articleFirst published February, 2024pp. 19-22
Addressing Scientific Misconduct: An Interview with Elisabeth Bik
Elisabeth BikUduak Thomas
News
Restricted accessNewsFirst published February, 2024pp. 23-25
Stretching the Limits of Bicyclic Peptides: A Novel Approach to MYC Inhibition and Beyond
Hugo ThabussotMarie-Eve BeaulieuLaura SoucekORCID
Review article
Restricted accessReview articleFirst published February, 2024pp. 26-28
The Curious Case of Katalin Karikó
Fay Lin
Research article
Restricted accessResearch articleFirst published February, 2024pp. 29-31
Meditations on Biotech Leadership
Angelos Georgakis
Research article
Restricted accessResearch articleFirst published February, 2024pp. 32-34
Obesity,Artificial Intelligence and More: Vijay Pande on 2024 in Biotech
Vijay PandeAlex Philippidis
Research article
Restricted accessResearch articleFirst published February, 2024pp. 35-44
A Fluorescent Sex-Sorting Technique for Insects with the Demonstration in Drosophila melanogaster
Junru LiuORCIDDanny RayesOmar S. AkbariORCID
Abstract
Recent advances in insect genetic engineering offer alternative genetic biocontrol solutions to control populations of pests and disease vectors. While success has been achieved, sex-sorting remains problematic for scaling many genetic biocontrol interventions. Here, we describe the development of a genetically stable sex-sorting technique for female and male selection with a proof of concept in Drosophila melanogaster termed SEPARATOR (Sexing Element Produced by Alternative RNA-splicing of A Transgenic Observable Reporter). This elegant approach utilizes dominantly expressed fluorescent proteins and differentially spliced introns to ensure sex-specific expression. The system has the potential for adaptability to various insect species and application for high-throughput insect sex-sorting.
Research article
Restricted accessResearch articleFirst published February, 2024pp. 45-45
Acknowledgment of Reviewers 2023

Volume 3, Issue 1, February 2024