In 1994 Amin et al. described an uncommon variant of urothelial carcinoma: the micropapillary carcinoma (MPC). The MPC of the urinary bladder is rare, but has an aggressive clinical course. The optimal treatment strategy for this tumor appears to be early radical cystectomy. We report a case of MPC of the urinary bladder and review the literature.
AminM.B., RoJ.Y., El SharkawyT.Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma.Am J Surg Pathol1994; 18: 1224–1232.
2.
MaranchieJ.K., BouyouneB.T., ZhangP.L., O'DonnellM., SumerhayesI.C., DewolfW.C.. Clinical and pathological characteristics of micropapillary transitional cell carcinoma: a highly aggressive variant.J Urol2000; 163: 748–51.
3.
KamatA.M., DinneyC.P., GeeI.R., GrossmanH.B., Siefker-RadtkeA.O., AmboliP.Micropapillary bladder cancer: a review of the University of Texas M.D Anderson Cancer Center experience with 100 consecutive patients.Cancer2007; 110(1): 62–7.
4.
JohanssonS.L., BorghedeG., HolmangS.. Micropapillary bladder carcinoma: a clinicopathological study of 20 cases.J Urol1999, 161(6): 1798–1802.
5.
Alvarado-Cabrero, Sierra-SantiestebanF.L., Mantilla-MoralesA.Micropapillary carcinoma of the urothelial tract. Aclinicopathologic study of 38 cases.Ann Diagn Pathol2005; 9: 1–5.
6.
ComperatE., RoupretM., YaxleyJ., ReynoldsJ., VarinotJ., OuzaidI.Micropapillary urothelial carcinoma of the urinary bladder: a clinicopathological analysis of 72 cases.Pathology2010; 42(7): 650–4.
7.
ShanksJ.H., IczkowskiK.A.. Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics.Hystopathology2009; 54(7): 885–900.
8.
HeudelP., El KarakF., IsmaiiN., DrozJ.P., FlechonA.. Micropapillary bladder cancer: a review of Leon Berard Cancer Center experience.BMC urol.2009; 9: 5.