High-frequency oscillatory ventilation (HFOV) can improve ventilation-perfusion matching without excessive alveolar tidal stretching or collapse-reopening phenomenon. This is an attractive feature in the ventilation of patients with ARDS. However, two recent large multi-center trials of HFOV failed to show benefits in this patient population. The following review addresses whether, in view of these trails, HFOV should be abandoned in the adult population?
ARDS Definition Task Force, RanieriVM, RubenfeldGD, ThompsonBT, FergusonND, CaldwellE, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA, 2012; 307(23):2526–2533.
3.
HerridgeMS, TanseyCM, MattéA, TomlinsonG, Diaz-GranadosN, CooperA, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med, 2011; 364(14):1293–1304.
4.
BrochardL, Roudot-ThoravalF, RoupieE, DelclauxC, ChastreJ, Fernandez-MondéjarE, et al. Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome. Am J Respir Crit Care Med, 1998; 158(6):1831–1838.
5.
Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med, 2000; 342(18):1301–1308.
6.
PetrucciN, De FeoC. Lung protective ventilation strategy for the acute respiratory distress syndrome. Cochrane Database Syst Rev. 2013;(2):CD003844.
7.
KrishnanJA, BrowerRG. High-frequency ventilation for acute lung injury and ARDS. Chest, 2000; 118(3):795–807.
8.
ChanKPW, StewartTE, MehtaS. High-frequency oscillatory ventilation for adult patients with ARDS. Chest, 2007; 131(6):1907–1916.
9.
RimensbergerPC, PacheJC, McKerlieC, FrndovaH, CoxPN. Lung recruitment and lung volume maintenance: a strategy for improving oxygenation and preventing lung injury during both conventional mechanical ventilation and high-frequency oscillation. Intensive Care Med, 2000; 26(6):745–755.
10.
ImaiY, SlutskyAS. High-frequency oscillatory ventilation and ventilator-induced lung injury. Crit Care Med, 2005; 33(3 Suppl):S129–S134.
11.
DavidM, WeilerN, HeinrichsW, NeumannM, JoostT, MarkstallerK, EberleB. High frequency oscillatory ventilation in adult acute respiratory distress syndrome. Intensive Care Med, 2003; 29(10):1656–1665.
12.
PillowJJ, NeilH, WilkinsonMH, RamsdenCA. Effect of I/E ratio on mean alveolar pressure during high-frequency oscillatory ventilation. J Appl Physiol, 1999; 87(1):407–414.
13.
LunkenheimerPP, RafflenbeulW, KellerH, FrankI, DickhutHH, FuhrmannC. Application of transtracheal pressure oscillations as a modification of “diffusing respiration”. Br J Anaesth, 1972; 44(6):627.
14.
ChangHK. Mechanisms of gas transport during ventilation by high frequency oscillation. J Appl Physiol Respir Environ Exerc Physiol, 1984; 56(3):553–563.
15.
RossingTH, SlutskyAS, LeherJL, LehrJL, DrinkerPA, KammR, DrazenJM. Tidal volume and frequency dependence of carbon dioxide elimination by high-frequency ventilation. N Engl J Med, 1981; 305(23):1375–1379.
16.
GoffiA, FergusonND. High-frequency oscillatory ventilation for early acute respiratory distress syndrome in adults. Curr Opin Crit Care, 2014; 20(1):77–85.
17.
HagerDN, FesslerHE, KaczkaDW, ShanholtzCB, FuldMK, SimonBA, BrowerRG. Tidal volume delivery during high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med, 2007; 35(6):1522–1529.
18.
IsabeyD, HarfA, ChangHK. Alveolar ventilation during high-frequency oscillation: core dead space concept. J Appl Physiol Respir Environ Exerc Physiol, 1984; 56(3):700–707.
19.
VitaliSH, ArnoldJH. Bench-to-bedside review: ventilator strategies to reduce lung injury: lessons from pediatric and neonatal intensive care. Crit Care, 2005; 9(2):177–183.
20.
CoolsF, OffringaM, AskieLM. Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in preterm infants. Cochrane Database Syst Rev, 2015;(3):CD000104.
21.
FortP, FarmerC, WestermanJ, JohannigmanJ, BeninatiW, DolanS, DerdakS. High-frequency oscillatory ventilation for adult respiratory distress syndrome: a pilot study. Crit Care Med, 1997; 25(6):937–947.
22.
SudS, SudM, FriedrichJO, WunschH, MeadeMO, FergusonND, AdhikariNK. High-frequency ventilation versus conventional ventilation for treatment of acute lung injury and acute respiratory distress syndrome. Cochrane Database Syst Rev, 2013;(2):CD004085.
23.
KacmarekRM, MalhotraA. High-frequency oscillatory ventilation: what large-animal studies have taught us!. Crit Care Med, 2005; 33(3 Suppl):S148–S154.
24.
AllenJL, FrantzID3rd, FredbergJJ. Heterogeneity of mean alveolar pressure during high-frequency oscillations. J Appl Physiol, 1987; 62(1):223–228.
25.
MehtaS, GrantonJ, MacDonaldRJ, BowmanD, Matte-MartynA, BachmanT, et al. High-frequency oscillatory ventilation in adults: the Toronto experience. Chest, 2004; 126(2):518–527.
26.
SedeekKA, TakeuchiM, SuchodolskiK, KacmarekRM. Determinants of tidal volume during high-frequency oscillation. Crit Care Med, 2003; 31(1):227–231.
27.
PapazianL, GainnierM, MarinV, DonatiS, ArnalJM, DemoryD, et al. Comparison of prone positioning and high-frequency oscillatory ventilation in patients with acute respiratory distress syndrome. Crit Care Med, 2005; 33(10):2162–2171.
28.
Vazquez de AndaGF, GommersD, VerbruggeSJC, De JaegereA, LachmannB. Mechanical ventilation with high positive end-expiratory pressure and small driving pressure amplitude is as effective as high-frequency oscillatory ventilation to preserve the function of exogenous surfactant in lung-lavaged rats. Crit Care Med, 2000; 28(8):2921–2925.
29.
GuervillyC, ForelJM, HraiechS, DemoryD, Allardet-ServentJ, AddaM., et al. Right ventricular function during high-frequency oscillatory ventilation in adults with acute respiratory distress syndrome. Crit Care Med, 2012; 40(5):1539–1545.
30.
MalhotraA, DrazenJM. High-frequency oscillatory ventilation on shaky ground. N Engl J Med, 2013; 368(9):863–865.
31.
FergusonND, CookDJ, GuyattGH, MehtaS, HandL, AustinP, et al. High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med, 2013; 368(9):795–805.
32.
YoungD, LambSE, ShahS, MacKenzieI, TunnicliffeW, LallR, et al. High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med, 2013; 368(9):806–813.
33.
MaitraS, BhattacharjeeS, KhannaP, BaidyaDK. High-frequency ventilation does not provide mortality benefit in comparison with conventional lung-protective ventilation in acute respiratory distress syndrome: a meta-analysis of the randomized controlled trials. Anesthesiology, 2015; 122(4):841–851.
34.
ChanKPW, StewartTE. Clinical use of high-frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome. Crit Care Med, 2005; 33(3 Suppl):S170–S174.
35.
DerdakS, MehtaS, StewartTE, SmithT, RogersM, BuchmanTG, et al. High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med, 2002; 166(6):801–808.
36.
FroeseAB, BryanAC. High frequency ventilation. Am Rev Respir Dis, 1987; 135(6):1363–1374.
37.
GoddonS, FujinoY, HromiJM, KacmarekRM. Optimal mean airway pressure during high-frequency oscillation predicted by the pressure-volume curve. Anesthesiology, 2001; 94(5):862–869.
38.
KoltonM, CattranCB, KentG, VolgyesiG, FroeseAB, BryanAC. Oxygenation during high-frequency ventilation compared with conventional mechanical ventilation in two models of lung injury. Anesth Analg, 1982; 61(4):323–332.
39.
LueckeT, MeinhardtJP, HermannP, HerrmannP, WeisserG, PelosiP, QuintelM. Setting mean airway pressure during high-frequency oscillatory ventilation according to the static pressure-volume curve in surfactant-deficient lung injury: a computed tomography study. Anesthesiology, 2003; 99(6):1313–1322.
40.
LueckeT, HerrmannP, KraincukP, PelosiP. Computed tomography scan assessment of lung volume and recruitment during high-frequency oscillatory ventilation. Crit Care Med, 2005; 33(3 Suppl):S155–S162.
41.
TakataM, AbeJ, TanakaH, KitanoY, DoiS, KohsakaT, MiyasakaK. Intraalveolar expression of tumor necrosis factor-gene during conventional and high-frequency ventilation. Am J Respir Crit Care Med, 1997; 156(1):272–279.
42.
SuzukiH, PapazoglouK, BryanAC. Relationship between PaO2 and lung volume during high frequency oscillatory ventilation. Acta Paediatr Jpn, 1992; 34(5):494–500.
43.
FroeseAB, KinsellaJP. High-frequency oscillatory ventilation: lessons from the neonatal/pediatric experience. Crit Care Med, 2005; 33(3 Suppl):S115–S121.
44.
AndersenFA, GuttormsenAB, FlaattenHK. High frequency oscillatory ventilation in adult patients with acute respiratory distress syndrome: a retrospective study. Acta Anaesthesiol Scand, 2002; 46(9):1082–1088.
45.
BollenCW, UiterwaalCS, van VughtAJ. Meta-regression analysis of high-frequency ventilation vs conventional ventilation in infant respiratory distress syndrome. Intensive Care Med, 2007; 33(4):680–688.
46.
YoungD, LambSE, ShahS, MacKenziI, TunnicliffeW, LallR, et al; OSCAR Study Group. High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med, 2013; 368(9):806–813.
47.
FergusonND, CookDJ, GuyattGH, MehtaS, HandL, AustinP, et al; OSCILLATE Trial Investigators; Canadian Critical Care Trials Group. High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med, 2013; 368(9):795–805.
48.
DerdakS, MehtaS, StewartTE, SmithT, RogersM, BuchmanTG, et al; Multicenter Oscillatory Ventilation For Acute Respiratory Distress Syndrome Trial (MOAT) Study Investigators. High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med, 2002; 166(6):801–808.
49.
SudS, SudM, FriedrichJO, MeadeMO, FergusonND, WunschH, AdhikariNK. High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis. Br J Med, 2010; 340:c2327–c2338.
50.
ArnoldJH, HansonJH, Toro-FigueroLO, GutierrezJ, BerensRJ, AnglinDL. Prospective, randomized comparison of high frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. Crit Care Med, 1994; 22(10):1530–1539.
51.
BollenCW, UiterwaalCS, van VughtAJ. Cumulative metaanalysis of high-frequency versus conventional ventilation in premature neonates. Am J Respir Crit Care Med, 2003; 168(10):1150–1155.
52.
FesslerHE, DerdakS, FergusonND, HagerDN, KacmarekRM, ThompsonBT, BrowerRG. A protocol for high-frequency oscillatory ventilation in adults: results from a roundtable discussion. Crit Care Med, 2007; 35(7):1649–1654.
53.
ChangHK. Mechanisms of gas transport during ventilation by high frequency oscillation. J Appl Physiol, 1984; 56(3):553–563.
