Abstract
In rabbits, auriculo-acupuncture electrostimulation with frequencies of 15 and 100 Hz induced an analgesic effect expressed by a decrease in tne amplitude of a cortical somatosensory evoked potential in response to tooth pulp electrostimulation. Intracerebroventricular saralasin injection abolished or blocked the effect of auriculo-acupuncture stimulation at 100 Hz, but not at 15 Hz frequency. Intravenous injection of naloxone abolished the effect of auriculo-acupuncture stimulation at 15 Hz but not at 100 Hz frequency. Methysergide or D, L-p-chlorophenylaianine injection diminished but did not entirely block the effect of auriculo-acupuncture stimulation at 100 Hz. This suggests that the neuropeptide angiotensin II is a antinociceptive factor in dental peptide analgesic mechanisms induced by auriculo-acupuncture stimulation at 100 Hz frequency.
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