An instrument consisting of a copper vapor laser coupled to an optical fiber/chemical injector catheter for the treatment of occluded arteries has been constructed and tested. The combined application of three steps: the pre-irradiation injection of a light absorbing dye, HPD; brief copper laser irradiation (at 578 nm); and a urokinase infusion after the irradiation, produced the striking effect of liquefaction and resolution of thrombus. The histological examination of the arteries after the treatment showed no apparent damage to the arterial wall.
ChoyDSI, “Fiber Optic Laser Tunneling Device: The Laser Catheter,” in Beijing Shanghai Proceedings of the International Conference on Lasers. Wiley-Interscience Publications, N.Y., pp. 685-690,1980.
2.
MarcruzRMartinsJRMTupinambaALopesEAVargasHPenaafDECarvalahoVBArmelinEDe’CourtLV, “Therapeutic Possibilités of Laser Beams in Atheromas.”Arq Bras Cardiol. 34:9-12,1980.
3.
MarcoJSilvernailPJFoumailGDanielSJChoyFajadet JCaseRB, “Complete Patency in Thrombus-Occluded Arteries Two Weeks After Laser Recanalization,”Lasers in Surgery and Medicine. 5:291-296, 1985.
4.
MacruzRRibeiroMPBrumJMGPasqualucciCAMnitentagJBozinisDGMarquesEJateneADDe’courtLVArmelinE“Laser Surgery in Enclosed Spaces: A Review.”Lasers in Surgery and Medicine. 5:199-218.1985.
5.
AbelaGCohenDFeldmanRLNormannSContiRCPpingCJ, “Use of Laser Radiation to Recanalize Stenosed Arteries in Living Rabbits,”Clinical Research. 31:23, Abstract 458A, 1983.
6.
SanbornTAFaxonDPHaudenshchildCCGottsmanSBRyanTJ, “Angiographic and Histopathologic Consequences of in Vivo Laser Radiation of Atherosclerotic Lesions,”American Heart Association 56th Scientific Sessions. Abstract 577, 1983.
7.
ChoyDSJStenzerSLoubeauJean-MichelKesselerHoward Quilici PhillipeRotterdamHeidrunMeltzerLon, “Embolization and Vessel Wall Perforation in Argon Laser Recanalization,”Lasers in Surgery and Medicine. 5:297-308, 1985.
8.
GessmanLJRenoCWChangKS, “Feasibility of Laser Catheter Valvulotomy for aortic and mitral stenosis”,American Journal of Cardiology. 54,1375-7,1984.
9.
CaseRBChoyDSJDwyerEMSilvernailPJ, “Absence of Distal Embolization During in Vivo Laser Recanalization,”Lasers in Surgery and Medicine. 5:281-189.1985.
ChoyDSJStenzerSHCaseRBMarcoJFoumailGSilvernailPJMylerRK, “Update on Laser Recanalization,”Lasers in Surgery and Medicine. 3(4): 357,1984.
12.
BemsMWWileADahlmantAJohnsonFBumsRSperlingBGuiltnanMSiemensAWalterRHammer-WilsonM : “Cellular Uptake, Excretion and Localization.”Advances in Experimental Medicine and Biology, 160: 139-150, Plenum Press, New York, 1983.
13.
KaminowIPWisenfeldJMChoyDSJ, “Argon Laser Disintegration of Thrombus and Atherosclerotic Plaque,”Applied Optics. Vol. 23, No. 9,1984.
14.
DoughertyTJBoyleDGWeishauptKRHendersonBAPotterWRBellnierDAWitykBE, “Photoradiation Tlierapy-Clinical and Drug,”Advances in Experimental Medicine and Biology. 160:3-14. Plenum Press, New York, 1983.
15.
SpearsJRSerurJShropshireDPaulinS“Fluorescence of Experimental Altheromatous Plaques with Hematoporphyrin Derivative (HPD),”Clin, Invest.,75: 395-399, 1983.
16.
DoironDRSvaasandLOProfioAE, “Light Dosimetry in Tissue: Appliction to Photoradiation Therapy,”Advances in Experimental Medicine and Biology. 160:63-76, Plenum Press, New York, 1983.
17.
ProfioA EdwardDoironDaniel R, “Dosimetry Considerations in Phototherapy,”Medical Physics. 8:191,1981.
18.
KatoHKonakaCOnoJMatsushimaYNishimiyaKLayJSawaHShinoharaHSaitoTKinoshitaKTomonoTAidaMHayataY, “Effectiveness of HPD and Radiation Therapy in Lung Cancer,”Advances in Experimental Medicine and Biology. 160:23-40, Plenum Press, New York, 1983.
