The balance of the intestinal microecosystem is essentially consistent with the theory of “Yin Ping Yang Mi” in Chinese medicine. The imbalance of the intestinal microenvironment's homeostasis is closely related to the occurrence of diseases. Acupuncture and moxibustion can improve the disease state by regulating the stability of the intestinal microecology, which has a certain theoretical basis. By exploring the law of the body's meridian circulation, it provides a theoretical basis for studying the regulation of acupuncture on the intestinal microecology of patients with knee osteoarthritis (KOA).
ZhuQLiu HG Intestinal Microecosystem and Common Digestive System Diseases: Intestinal Microecosystem and Intestinal Mucosal Barrier. Shandong Medicine51(35)10O, 2011
2.
WenJYTang HZ Effects of Acupuncture on Intestinal Flora Regulation. Guangxi Medical Journal40(22)2714-2716, 2018
3.
Mayer EA Gut Feelings: The Emerging Biology of Gut Brain Communication. Nature Neuroscience 12(8)453-66, 2011
4.
WeiWRongPJChenJD. Discussion and Construction of the Theory of “Adjusting the Central Axis and Promoting the Stomach”. Journal of Traditional Chinese Medicine59(06)474–477+502, 2018
5.
XieLLResearch Progress on the Relationship between Intestinal Flora and Disease. Genomics and Applied Biology36(11)4570–4573, 2017
6.
ZackularJPBaxterNTIversonKD. The Gut Microbiome Modulates Colon Tumorigenesis. MBio 4:e00692-13, 2013
7.
BarbaraGFeinleBCGhoshalUC. The Intestinal Microenvironment and Functional Gastrointestinal Disorders. Gastroenterology150(6)1305–1318, 2016
8.
Freestone PPE, SandriniSMHaighRD. Microbial Endocrinology: How Stress Influences Susceptibility to Infection. Trends in Microbiology16(2)55–64, 2008
9.
SantistebanMMQiYFZubcevicJ. Hypertension-Linked Pathophysiological Alterations in the Gut. Circulation Research120:312–323, 2017
10.
LiuCHYangXQLiuEM. Effects of Antibiotics on Immune Function and Toll-like Receptor 2 and 4 Gene Expression in Mice. Journal of Chongqing Medical University32(8)839–842, 2007
11.
WuGLDiscussion on the Essence of Traditional Chinese Medicine in Intestinal Microecology. Chinese Journal of Traditional Chinese Medicine33(11)2586–2588, 2015
12.
Liu SK The Application of Qi Machine Lifting Theory in Clinical Acupuncture and Moxibustion. Beijing Traditional Chinese Medicine 32(5)364-365, 2013
13.
Qin PL Thinking on the Regulation of Intestinal Flora by Acupuncture and Moxibustion based on Brain-gut Axis Theory. Shizhen TCM and TCM 26(11)2712-2714, 2015
14.
SunSXBai XX Understanding of Brain-gut Axis from the Perspective of Physiology and Pathology of Traditional Chinese Medicine. Shaanxi Journal of Traditional Chinese Medicine38(06)787-788, 2017
15.
Guo XZ Basic Theory of TCM. Shanghai: Shanghai Science and Technology Press, 136–137, 2006
16.
YinTSunRRHeZX. Discussion on “Large Intestine and Small Intestine belong to Stomach”. Hunan Journal of Chinese Medicine32(11)138–140, 2016
17.
HuangKYLiangSFuSP. Discussion on the Application of Gastrointestinal Conditioning in the Treatment of Encephalopathy by Acupuncture and Moxibustion based on the Theory of Brain-gut Axis. Journal of Traditional Chinese Medicine57(13)1099-1104, 2016
18.
SuantaweeTTantavisutSAdisakwattanaS. Oxidative Stress, Vitamin E an. Antioxidant Capacity in Knee Osteoarthritis. Journal of Clinical and Diagnostic Research7(9)1855-9, 2013
19.
VincentHKPercivalSSConradBP. Hyaluronic Acid (HA) Visco Supplementation on Synovial Fluid Inflammation in Knee Osteoarthritis: A Pilot Study. Open Orthopaedics Journal7:378–84, 2013
20.
LivshitsGZhaiGHartDJ. Interleukin-6 is a Significant Predictor of Radiographic Knee Osteoarthritis: The Chingford Study. Arthritis & Rheumatology60(7)2037-45, 2009
21.
HuangZYKraus VB Does Lipopolysaccharide-mediated Inflammation Have a Role in OA? Nature Reviews Rheumatology12:123–9, 2016
22.
CoulsonSButtHVecchioP. Green-lipped Mussel Extract (Perna canaliculus) and Glucosamine Sulphate in Patients with Knee Osteoarthritis: Therapeutic Efficacy and Effects on Gastrointestinal Microbiota Profiles. Inflammopharmacology21(1)79–90, 2013
23.
LiYWeiLDe ngZ. Diet-Intestinal Microbiota Axis in Osteoarthritis: A Possible Role. Mediators of Inflammation 3495173, 2016
24.
MuccioliGGNaslainDCkhedFB. The Endocannabinoid System Links Gut Microbiota to Adipogenesis. Molecular Systems Biology6(1)392-405, 2010
25.
PuenpatomRAVictor TW Increased Prevalence of Metabolic Syndrome in Individuals with Osteoarthritis: An Analysis of NHANES III Data. Postgraduate Medicine121(6)91-104, 2009
26.
CollinsKHPaulHAReimerRA. Relationship between Inflammation, the Gut Microbiota, and Metabolic Osteoarthritis Development: Studies in a Rat Model. Osteoarthritis and Cartilage23(11)1989-1995, 2015
27.
HuangZYStablerTPeiFX. Both Systemic and Local Lipopolysaccharide (LPS) Burden are Associated with Knee OA Severity. Osteoarthritis and Cartilage24(10)1769-1775, 2016
28.
BoerCGRadjabzadehDMedina-GomezC. Intestinal Microbiome Composition and its Relation to Joint Pain and Inflammation. Nature Communications 10:4881, 2019
29.
LiYTShiGXTuJF. Analysis on the Rule of Acupuncture and Moxibustion Treatment of Knee Osteoarthritis. Liaoning Journal of Traditional Chinese Medicine44(10)2179–2182, 2017
30.
PengXStudy on the Relationship between Yangming and Taiyin Syndrome and Intestinal Microecology and Human Response. Beijing: Beijing University of Chinese Medicine, 30–34, 2008
31.
NingYLCheng ZD Discussion on the Relationship Between Acupuncture and Intestinal Flora from the Theory of Qi Machine Lifting and Lowering. Journal of Traditional Chinese Medicine58(01)31–33, 2017
32.
WangTQShiGXYangNN. Discussion on the Theoretical Basis for Acupuncture to Improve Knee Osteoarthritis based on the Theory of “Brain Gut Axis”. Hebei Journal of Traditional Chinese Medicine34(5)61-64, 2019
33.
GoldmanNChenMFujitaT. Adenosine A1 Receptors Mediate Local Anti-Nociceptive Effects of Acupuncture. Nature Neuroscience13:883–8, 2010
34.
Liang M Regulation Effect of Acupuncture Treatment on Intestinal Flora of Patients with Simple Obesity. Nanning: Guangxi University of Traditional Chinese Medicine 26–28, 2016
