The mechanisms of ion exchanges and water fluxes underlying the endolymphatic hydrops phenomenon, remain indeterminate so far. This review intends to reposition the physical environment of the endolymphatic compartment within the inner ear, as well as to recall the molecular effectors present in the membranous labyrinth and that could be at the source of the hydrops.
AhnS.K. and BalabanC.D., Distribution of 5-HT1B and 5-HT1D receptors in the inner ear, Brain Res1346 (2010), 92–101. doi: 10.1016/j.brainres.2010.05.057
2.
AndrewsJ.C. and BöhmerA., The surgical approach to the endolymphatic sac and the cochlear aqueduct in the guinea pig, Am J Otolaryngol10(1) (1989), 61–6. doi: 10.1016/0196-0709(89)90093-8. PMID: 2929878
3.
AttyéA., EliezerM., MediciM., et al., In vivo imaging of saccular hydrops in humans reflects sensorineural hearing loss rather than Meniere’s disease symptoms, Eur Radiol28 (2018), 2916–2922. doi: 10.1007/s00330-017-5260-7
4.
BartolamiS., GaboyardS., QuentinJ., et al., Critical roles of transitional cells and Na/K-ATPase in the formation of vestibular endolymph, Journal of Neuroscience31 (2011), 16541–9.
5.
BreuerJ., Uber die Bogeng ange das Labyrinths: Vorl’aufige Mitteilung, Anz Ges d’Arzte7 (1883), 15–18.
6.
BreuerJ., Uber die Function der Bogeng¨ange des Ohrlabyrinthes, Wien Med Jahrb4 (1884), 72–124.
7.
DongS.H., KimS.S., KimS.H. and YeoS.G., Expression of aquaporins in inner ear disease, Laryngoscope (2019). doi: 10.1002/lary.28334
8.
FauserC., SchimanskiS. and WangemannP., Localization of beta1-adrenergic receptors in the cochlea and the vestibular labyrinth, J Membr Biol201 (2004), 25–32. doi: 10.1007/s00232-004-0703-x
9.
FitzgeraldD.C. and YamakawaK., Temporal bone histopathology of Meniere’s patient reported in 1938, Arch Otolaryngol Head Neck Surg119 (1993), 1383. doi: 10.1001/archotol.1993.01880240123019
10.
GaboyardS., ChabbertC., TravoC., et al., Three dimensional culture of newborn rat utricle with extracellular matrix: A new functional in vitro model, Neuroscience133 (2005), 253–265.
11.
GentineA., MartinE., SchultzP., DebryC. and CharpiotA., Lateral semicircular canal plugging: a simple and effective surgical treatment against incapacitating Menière’s disease, Rev Laryngol Otol Rhinol (Bord)129 (2008), 11–16. Bas du formulaire.
12.
GleiserC., WagnerA., Fallier-BeckerP, WolburgH., HirtB. and MackA.F., Aquaporin-4 in astroglial cells in the CNS and supporting cells of sensory organs - A comparative perspective, Int J Mol Sci17 (2016), pii: E1411. doi: 10.3390/ijms17091411
13.
GoltzF., Uber die physiologische Bedeutung der Bogeng ange des Ohrlabyrinthes, Arch Physiol3 (1870), 172–192.
14.
HallpikeC.S. and CairnsH., Observations on the Pathology of Ménière’s Syndrome: (Section of Otology), Proc R Soc Med31 (1938), 1317–1336.
15.
HudspethA.J., How the ears works work?Nature381 (1989), 397–404.
16.
JiangL.Y., HeJ.J., ChenX.X., SunX.J., WangX.Z., ZhongS. and ChenH.D., Arginine Vasopressin-Aquaporin-2 Pathway-Mediated Dehydration Effects of Electroacupuncture in Guinea Pig Model of AVP-Induced Endolymphatic Hydrops, Chin J Integr Med25(10) (2019), 763–769. doi: 10.1007/s11655-017-2411-2. Epub 2018 Jan 15. PMID: 29335859.
17.
KakigiA., NishimuraM., TakedaT., TaguchiD. and NishiokaR., Expression of aquaporin1, 3, and 4, NKCC1, and NKCC2 in the human endolymphatic sac, Auris Nasus Larynx36 (2009), 135–139. doi: 10.1016/j.anl.2008.04.012
18.
KimM. and KimK.S., Vestibular Function Change in a Vasopressin-Induced Hydrops Model, Otol Neurotol38(10) (2017), e495–e500.
19.
KimB.G., KimJ.Y., JungJ., MoonI.S., YoonJ.H., ChoiJ.Y. and KimS.H., β1- and β2-adrenergic stimulation-induced electrogenic transport by human endolymphatic sac epithelium and its clinical implications, Sci Rep7 (2017), 42217.
20.
KimK.X. and MarcusD.C., Inward-rectifier chloride currents in Reissner’s membrane epithelial cells, Biochem Biophys Res Commun394(2) (2010), 434–438.
21.
KimK.X., SannemanJ.D., KimH.M., HarbidgeD.G., XuJ., SoleimaniM., WangemannP. and MarcusD.C., Slc26a7 chloride channel activity and localization in mouse Reissner’s membrane epithelium, PLoS One9(5) (2014), e97191.
22.
KimS.H. and MarcusD.C., Endolymphatic sodium homeostasis by extramacular epithelium of the saccule, J Neurosci29(50) (2009), 15851–8. doi: 10.1523/JNEUROSCI.3044-09.2009
23.
KimS.H. and MarcusD.C., Regulation of sodium transport in the inner ear, Hear Res280(1-2) (2011), 21–29.
24.
KimS.H., NamG.S. and ChoiJ.Y., Pathophysiologic Findings in the Human Endolymphatic Sac in Endolymphatic Hydrops: Functional and Molecular Evidence, Ann Otol Rhinol Laryngol128(6_suppl) (2019), 76S–83S. doi: 10.1177/0003489419837993. PMID: 31092029
25.
KimS.H., ParkH.Y., ChoiH.S., ChungH.P. and ChoiJ.Y., Functional and molecular expression of epithelial sodium channels in cultured human endolymphatic sac epithelial cells, Otol Neurotol30(4) (2009), 529–534. doi: 10.1097/MAO.0b013e31819a8e0e. PMID: 19300301
26.
KimuraR.S., Animal models of endolymphatic hydrops, Am J Otolaryngol3 (1982), 447–451. doi: 10.1016/s0196-0709(82)80023-9
27.
MatsubaraA., MiyashitaT., InamotoR. and MoriN., Presence of adrenergic receptors in rat endolymphatic sac epithelial cells, J Membr Biol246 (2013), 109–114. doi: 10.1007/s00232-012-9508-5
28.
McCullarJ.S. and OesterleE.C., Cellular targets of estrogen signaling in regeneration of inner ear sensory epithelia, Hear Res252 (2009), 61–70. doi: 10.1016/j.heares.2009.01.012
29.
MenièreP., Mémoire sur des lésions de l’oreille interne donnant lieu à des symptômes de congestion cérébrale apoplectiforme, lu à l’académie impériale de Médecine, séance du 8 janvier, 1861.
30.
MilhaudP.G., SatyanarayanaR.P., Ho LeeJ, HerzogM., LehouelleurJ., WangemannP., SansA. and MarcusD.C., Chloride secretion by semicircular canal duct epithelium is stimulated via ß2-adrenergic receptors, Am J Physiol Cell Physiol283 (2002), C1752–C1760.
31.
MinorL.B., SolomonD., ZinreichJ.S. and ZeeD.S., Sound- and/or pressure-induced vertigo due to bone dehiscence of the superior semicircular canal, Arch Otolaryngol Head Neck Surg124 (1998), 249–258. doi: 10.1001/archotol.124.3.249
32.
MøllerM.N., KirkebyS., VikesåJ., NielsenF.C. and Caye-ThomasenP., Expression of histamine receptors in the human endolymphatic sac: the molecular rationale for betahistine use in Menieres disease, Eur Arch Otorhinolaryngol273 (2016), 1705–1710.
33.
PortmannG., The saccus endolymphaticus and an operation for draining the same for the relief of vertigo 1927, J Laryngol Otol105 (1991), 1109–1112. doi: 10.1017/s0022215100118365
34.
SaltA.N. and PlontkeS.K., Endolymphatic hydrops: pathophysiology and experimental models, Otolaryngol Clin North Am43(5) (2010), 971–83. doi: 10.1016/j.otc.2010.05.007. PMID: 20713237; PMCID: PMC2923478
35.
ShiX., Pathophysiology of the cochlear intrastrial fluid-blood barrier, Hear Res338 (2016), 52–63. doi: 10.1016/j.heares.2016.01.010
36.
SonE.J., MoonI.S., KimS.H., KimS.J. and ChoiJ.Y., Interferon-gamma suppresses Na+-H+exchanger in cultured human endolymphatic sac epithelial cells, J Cell Biochem107(5) (2009), 965–72. doi: 10.1002/jcb.22201. PMID: 19479940
37.
SotoE., VegaR. and SeseñaE., Neuropharmacological basis of vestibular system disorder treatment, J Vestib Res23 (2013), 119–137. doi: 10.3233/VES-130494
38.
SunW. and WangW., Advances in research on labyrinth membranous barriers, J Otol3 (2015), 99–104. doi: 10.1016/j.joto.2015.11.003
39.
TakimotoY., IshidaY., NakamuraY., et al., 5-HT(3) receptor expression in the mouse vestibular ganglion, Brain Res1557 (2014), 74–82. doi: 10.1016/j.brainres.2014.02.016
40.
TakumidaM., KakigiA., EgamiN., NishiokaR. and AnnikoM., Localization of aquaporins 1, 2, and 3 and vasopressin type 2 receptor in the mouse inner ear, Acta Otolaryngol132 (2012), 807–813. doi: 10.3109/00016489.2012.662718
41.
WangemannP., LiuJ., ShimozonoM., SchimanskiS. and ScofielM.A., K+ secretion in strial marginal cells is stimulated via beta 1-adrenergic receptors but not via beta 2-adrenergic or vasopressin receptors, J Membr Biol175 (2000), 191–202.
42.
WardB.K., Otero-MillanJ, JareonsettasinP., et al., Magnetic vestibular stimulation (MVS) as a technique for understanding the normal and diseased labyrinth, Front Neurol8 (2017), 122. doi: 10.3389/fneur.2017.00122
43.
WuY.X., ZhuG.X., LiuX.Q., SunF., ZhouK., WangS., WangC.M., JiaJ.W., SongJ.T. and LuL.J., Noise alters guinea pig’s blood-labyrinth barrier ultrastructure and permeability along with a decrease of cochlear Claudin-5 and Occludin, BMC Neuroscience15 (2014), 136 doi: 10.1186/s12868-014-0136-0
44.
ZhangJ., ChenS., HouZ., CaiJ., DongM. and ShiX., Lipopolysaccharide-induced middle ear inflammation disrupts the cochlear intra-strial fluid-blood barrier through down-regulation of tight junction proteins, PlosOne10 (2015), 3:e0122572. doi: 10.1371/journal.pone.0122572.