Abstract
The method of applying fibrin sealants may affect their physical properties and surgical performance. In this study, the characteristics of a novel fibrin-sealant application system (Vivostat®) were compared with conventional fibrin sealant spray systems. Delivery rates of Vivostat were highly reproducible in both high and low delivery modes (coefficient of variation [CV] < 1.0%) Airflow rates of Vivostat were 578 ml/min (6.6% (6.5% were lower and less variable than conventional systems, which ranged from 5,000 to 10,000 ml/min depending on the pressure. Spray forces of Vivostat were conseqently lower than other systems and the deposited fibrin films formed were of more consistent thickness. Unlike other systems, blockages with Vivostat were rare on intermittent use. The Vivostat system offers the surgeon a controlled, precise and efficient means of fibrin sealant application with potential performance advantages over conventional spray application systems.
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