Background: The anterior cingulate cortex (ACC) has been implicated in both
cognitive and emotional processing, with cognitive information proposed to be processed
through the dorsal/caudal ACC and emotional information through the rostral/ventral
ACC.
Objective: The objective of this study is to investigate the role of the
dorsal anterior cingulate cortex (dACC) in cognitive and emotional processing using a
cognitive and emotional counting Stroop task in two patients in whom abnormalities in the
dACC were identified and treated.
Methods: Two patients performed the cognitive and emotional counting Stroop
task before and after treatment to examine whether the dACC has a specific or more general
processing function.
Results: We observed an overall improvement in the emotional, cognitive, and
neutral trials of the counting Stroop task after the intervention, indicating that the
dACC is not a subregion of the ACC that only contributes to a specific domain.
Conclusion: This study reveals that the dACC is not just a subregion of the
ACC that contributes to a specific cognitive function, but is rather part of a salience
network that influences general brain functioning, influencing cognitive as well as
emotional processing.
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