In this issue, Zakharova et al. report on important findings concerning the association between body mass index and dementia risk as related to sex. Concretely, underweight was strongly associated with dementia risk in men but not in women. We compare the results of this study with a recent publication by Jacob et al. and consider the role of sex in the association between body mass index and dementia.
KivimäkiM, LuukkonenR, BattyGD, FerrieJE, PenttiJ, NybergST, ShipleyMJ, AlfredssonL, FranssonEI, GoldbergM, KnutssonA, KoskenvuoM, KuosmaE, NordinM, SuominenSB, TheorellT, VuoksimaaE, WesterholmP, WesterlundH, ZinsM, KivipeltoM, VahteraJ, KaprioJ, Singh-ManouxA, JokelaM (2018) Body mass index and risk of dementia: Analysis of individual-level data from 1.3 million individuals. Alzheimers Dement14, 601–609.
2.
ZakharovaA, KitamuraK, WatanabeY, KabasawaK, TakahashiA, SaitoT, KobayashiR, OshikiR, TakachiR, TsuganeS, YamazakiO, WatanabeK, NakamuraK (2023) Sex differences in the association between body mass index and dementia risk in community-dwelling Japanese people aged 40–74 years. J Alzheimers Dis94, 949–959.
3.
JacobL, SmithL, KoyanagiA, KonradM, HaroJM, ShinJI, KostevK (2022) Sex-differential associations between body mass index and the incidence of dementia. J Alzheimers Dis88, 631–639.
