The long-term effects of repetitive head trauma on the brain have often been studied in boxers and American football players. The medical literature on this topic was reviewed in order to compare the findings related to boxing with those related to football. The evidence gathered from this review indicates that there are significant differences between the clinical and neuropathological descriptions of the chronic brain damage reported in retired boxers compared to those reported in retired football players. Differing biomechanics of head impacts in the two sports may help explain the different clinical and neuropathological consequences of participation in boxing versus football.
CassonIR, SiegelO, ShamR, CambellE, TarlauM, DiDomenicoA (1984) Brain damage in modern boxers. JAMA251, 2663–2667.
17.
RobertsGW, AllsopD, BrutonC (1990) The occult aftermath of boxing. J Neurol Neurosurg Psychiatry53, 373–378.
18.
OmaluBI, DeKoskyST, MinsterRL, KambohMI, HamiltonRL, WechtCH (2005) Chronic traumatic encephalopathy in a National Football League player. Neurosurgery57, 128–134.
19.
CassonIR, PellmanEJ, VianoDC (2006) Letter-to-Editor: Chronic traumatic encephalopathy in a National Football League player. Neurosurgery58, E1003, author reply E1003, discussion E1003.
20.
CassonIR, PellmanEJ, VianoDC (2006) 2nd Letter-to-Editor: Chronic traumatic encephalopathy in a National Football League player. Neurosurgery59, E1152.
21.
GuskiewiczKM, MarshallSW, BailesJ, McCreaM, CantuRC, RandolphC, JordanBD (2005) Association between recurrent concussion and late-life cognitive impairment in retired professional football players. Neurosurgery57, 719–726.
22.
OmaluBI, DeKoskyST, HamiltonRL, MinsterRL, KambohMI, ShakirAM, WechtCH (2006) Chronic traumatic encephalopathy in a National Football League player: Part II. Neurosurgery59, 1086–1092.
23.
GuskiewiczKM, MarshallSW, BailesJ, McCreaM, HardingHPJr, MatthewsA, MihalikJR, CantuRC (2007) Recurrent concussion and risk of depression in retired professional football players. Med Sci Sports Exerc39, 903–909.
24.
McKeeAC, CantuRC, NowinskiCJ, Hedley-WhyteET, GavettBE, BudsonAE, SantiniVE, LeeHS, KubilusCA, SternRA (2009) Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol68, 709–735.
25.
OmaluBI, HamiltonRL, KambohMI, DeKoskyST, BailesJ (2010) Chronic traumatic encephalopathy (CTE) in a National Football League Player: Case report and emerging medicolegal practice questions. J Forensic Nurs6, 40–46.
26.
OmaluB, BailesJ, HamiltonRL, KambohMI, HammersJ, CaseM, FitzsimmonsR (2011) Emerging histomorphologic phenotypes of chronic traumatic encephalopathy in American athletes. Neurosurgery69, 173–183.
27.
OmaluBI, BailesJ, HammersJL, FitzsimmonsRP (2010) Chronic traumatic encephalopathy, suicides and parasuicides in professional American athletes: The role of the forensic pathologist. Am J Forensic Med Pathol31, 130–132.
HartJJr, KrautMA, WomackKB, StrainJ, DidehbaniN, BartzE, ConoverH, MansinghaniS, LuH, CullumM (2013) Neuroimaging of cognitive dysfunction and depression in aging retired National Football League players: A cross-sectional study. JAMA Neurol70, 326–335.
30.
CassonIR, VianoDC, HaackeEM, KouZ, LeStrangeDG (2014) Is there chronic brain damage in retired NFL Players? Neuroradiology, neuropsychology and neurology examinations of 45 retired players. Sports Health6, 384–395.
31.
McKeeAC, CairnsNJ, DicksonDW, FolkerthRD, KeeneCD, LitvanI, PerlDP, SteinTD, VonsattelJP, StewartW, TripodisY, CraryJF, BieniekKF, Dams-O’ConnorK, AlvarezVE, GordonWA; TBI/CTE group (2016) The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Acta Neuropathol131, 75–86.
AvivR, TomlinsonG, KendallB, ThakkarC, ValentineA (2010) Cavum septi pellucidi in boxers. Can Assoc Radiol J61, 29–32.
40.
AthaJ, YeadonMR, SandoverJ, ParsonsKC (1985) The damaging punch. Br Med J1, 756–757.
41.
JochW, FritcheP, KrauseI (1981) Biomechanical analysis of boxing. In “” VII-A, 7th International Congress of Biomechanics,
MoreckiK,
FideliusK,
KdziorK,
WitA, eds. Baltimore MD, University Press. pp. 343–349.
42.
SmithMS, DysonRJ, HaleT, JanawayL (2000) Development of a boxing dynamometer and its punch force discrimination efficacy. J Sports Sci18, 445–450.
43.
WalilkoTJ, VianoDC, BirCA (2005) Biomechanics of Olympic boxer punches to the face. Br J Sports Med39, 710–719.
44.
VianoDC, CassonIR, PellmanEJ, BirCA, ZhangL, ShermanD, BoitanoM (2005) Concussion in professional football: Comparison with boxing head impacts – Part 10. Neurosurgery57, 1154–1173.
45.
PellmanEJ, VianoDC, TuckerAM, CassonIR, WaeckerleJF (2003) Concussion in professional football: Reconstruction of game impacts and injuries. Neurosurgery53, 799–814.
46.
PellmanEJ, VianoDC, TuckerAM, CassonIR, WaeckerleJF (2003) Concussion in professional football: Location and direction of helmet impacts – Part 2. Neurosurgery53, 1328–1341.
47.
VianoDC, CassonIR, PellmanEJ (2007) Concussion in professional football: Biomechanics of the struck player – Part 14. Neurosurgery61, 313–328.
48.
SanchezEJ, GablerLF, GoodAB, FunkJR, CrandallJR, PanzerMB (2018) A reanalysis of football impact reconstructions for head kinematics and finite element modeling. Clin Biomech (Bristol, Avon). doi: 10.1016/j.clinbiomech.2018.02.019
49.
KahnR (1999) A Flame of Pure Fire – Jack Dempsey and the Roaring ’20s. Harcourt Brace, New York.
