Abstract
Aging research is entering in an exciting moment due to the identification of genes and pathways that modulate this process. This has been elucidated in lower eukaryotic organisms, mainly in yeast and in the nematode Caenorhabditis elegans. These studies have suggested that metabolic capacity, efficiency of stress responses and genetic regulation play an important role in determining life span, and signal transduction pathways clearly regulate these processes. Similar pathways exist in mammals and some of them might also regulate their pace of aging.
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