Abstract
Erythrocyte deformability indexes and some hematologic parameters of Thyroxine (T4) treated guinea pigs (n=12) were compared with the data obtained from a control group (n=11). Both T3 and T4 levels of the T4 treated animals were found to be significantly higher than the levels measured in the control group. Red blood cell counts, hemoglobin and hematocrit values were higher in the hyperthyroid animals, while mean corpuscular volume in this group was significantly lower than the control group. On the other hand, mean indexes were found to be increased significantly in the T4 treated group. The change in mean corpuscular hemoglobin concentration and expected change in cytoplasmic viscosity of erythrocytes might explain the impairment in deformability.
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