Erythrocyte deformability (ED) and oxidative sensitivity (OS) in haemodialysis patients (HD)

Abstract

Oxidative sensitivity, measured by a modified ascorbate cyanide test, GSH and 51 Cr-RBC cytotoxicity, was abnormal before the haemodialysis. This increases after 30 min. dialysis, just behind the leukocytes drop. Biocompatible dialysis membranes do attenuate this phenomenon. All are indicative of RBC scavenger function against toxic oxygen radical production in dialysis patients. Despite this abnormality, erythrocyte deformability was completely normal.

Keywords

Oxidative sensitivity toxic oxygen radical haemodialysis erythrocyte deformability scavenger

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