Abstract
A study of the relationship between erythrocyte mean cell volume (MCV) and erythrocyte elongation (EI max) in the Ektacytometer has been made in healthy controls [58], arterial disease [40], renal disease [33], diabetes mellitus [32], Raynaud’s phenomenon [16], and liver disease [30]. There was a significant correlation between MCV and EI max in the 58 healthy controls (r = 0.574, p < 0.001) and in each of the clinical groups, with the exception of liver disease in which abnormal erythrocyte morphology independently influenced EI max. Correction of EI max for MCV, using a regression line, increases the specificity of erythrocyte elongation measurements for a loss of erythrocyte deformability.
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