Abstract
5-(2-Nitroalkyl)isopropylidene malonate and 5,5′-(2-nitro-1,3-propylidene)bis(isopropylidene malonate) were easily synthesised by one-pot tandem reaction of substituted Meldrum's acids with the aminomethylating agent (Me2NCH2OAc) and nitroalkanes in the presence of a weak acid, such as acetic acid.
References
1.
Meldrum A.N.
, J. Chem. Soc. , 1908 , 93 , 598 .
2.
McNab H.
, Chem. Soc. Rev. , 1978 , 7 , 345 .
3.
Chen B.C.
, Heterocycles , 1991 , 32 , 529 .
4.
Dumas A.M.
, and
Fillion E.
, Acc. Chem. Res. , 2010 , 43 , 440 .
5.
Pihlaja K.
, and
Seilo M.
, Acta Chem. Scand. , 1968 , 22 , 3053 .
6.
Chhabra R.
,
Bolte M.L.
, and
Crow W.D.
, Aust. J. Chem. , 1948 , 37 , 1795 .
7.
Yang G.S.
,
Shi J.H.
, and
Zhou Y.
, Youji Huaxue , 2002 , 22 , 525 .
8.
Li J.H.
, and
Chen Z.C.
, Synth. Commun. , 2000 , 30 , 2317 .
9.
Chen Z.C.
,
Li J.H.
, and
Su W.K.
, Synth. Commun. , 2001 , 31 , 409 .
10.
Li J.H.
, and
Li Z.G.
, Youji Huaxue , 2005 , 25 , 208 .
11.
Ballini R.
,
Palmieri A.
, and
Righi P.
, Tetrahedron , 2007 , 63 , 12099 .
12.
Eberle M.
, and
Lawton R.G.
, Helv. Chim. Acta. , 1988 , 71 , 1974 .
13.
Li J.H.
,
He J.H.
, and
Jin Z.M.
, Acta Cryst. , 2005 , 61 , 3106 .
14.
Umemiya S.
,
Nishino K.
,
Sato I.
, and
Hayashi Y.
, Chem. Eur. J. , 2014 , 20 , 15753 .
15.
Li J.H.
,
Chen Z.C.
, and
Li Y.
, J. Chem. Res. , 2004 , 356 .
16.
Gyoergy T.
,
Katalin E.K.
,
Ildiko M.B.
,
Sandor M.
,
Laszlo D.
,
Tamas F.
,
Eva M.K.
,
Karolyne M.
,
Marta P.
, and
Tivadar T.
, P. HU, 225528, 1997 . https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=15&ND=3&adjacent=true&locale=en_EP&FT=D&date=20070129&CC=HU&NR=225528B1&KC=B1