AbstractThree-component condensation of substituted Meldrum's acids with methyl ketones and aminomethylating agent in present of carboxylic anhydride, such as acetic anhydride, gives 5-(3-oxoalkyl)Meldrum's acids.KeywordsMannich basesMeldrum's acidmethyl ketonescondensationReferences1. Jing-Hua Li , Zhen-Chu Chen , Synth. Commun., 2000, 30, 2317.2. McNab H. , Chem. Soc. Rev., 1978, 7, 345.3. Jing-Hua Li , Zhen-Chu Chen , and Wei-Ke Su , Synth. Commun., 2001, 31, 409.4. Chhabra R. , Bolte M. L. , and Crow W. D. , Aust. J. Chem., 1984, 37, 1795.5. List B. , and Castello C. , Syn. Lett., 2001, 11, 1687.
