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Abstract

A three-component one-pot condensation of 2-[2-(4-chlorophenyl)-2-oxoethyl)]isoquinolinium bromide with benzo[1,3]dioxol-5-ol and an aromatic aldehyde in the presence of catalytic amounts of 1,4-diaza-bicyclo[2.2.2]octane (DABCO) in refluxing water gives trans-(4-chlorophenyl)-7-aryl-6,7-dihydro-[1,3]dioxolo[4,5-f]benzofuran-6-yl)methanone in excellent yield and in short time.

Keywords

DABCO green chemistry diastereoselectivity 4-chlorophenacyl bromide benzo[1,3]dioxol-5-ol

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DABCO as an Efficient Catalyst for the Diastereoselective Synthesis of trans -(4-chlorophenyl)-7-aryl-6,7-dihydro-[1,3]dioxolo[4,5- f ]benzofuran-6-yl) Methanone in an Aqueous Medium

Abstract

Keywords

References