A simple, efficient and high yielding one-pot protocol for the synthesis of oxospirotricyclic furobarbiturates was developed by pseudo three-component domino coupling of barbituric acids and various benzaldehydes in water, catalysed by molecular iodine.
ElinsonM.N., VereshchaginA. N., StepanovN. O., BelyakovP. A., and NikishinG. I., Tetrahedron Lett., 2010, 51, 6598.
8.
VereshchaginA.N., ElinsonM. N., DorofeevaE. O., ZaimovskayaT. A., StepanovN. O., GorbunovS. V., BelyakovP. A., and NikishinG. I., Tetrahedron, 2012, 68, 1198.
9.
TeimouriM.B., Akbari-MoghaddamP., and MotaghinezhadM., Tetrahedron, 2013, 64, 6804.
10.
TeimouriM.B., AbbasiT., and KhavasiH. R., J. Chem. Res., 2010, 34, 310.
11.
TeimouriM.B., AbbasiT., and MivehchiH., Tetrahedron, 2008, 64, 10425.
12.
TeimouriM.B., and BazhrangR., Monatsh. Chem., 2008, 139, 957.
13.
TeimouriM.B., and MivehchiH., Synth. Commun., 2005, 35, 1835.
14.
SheldonR.G., Green Chem., 2005, 7, 267.
15.
DebM., and BhuyanP. J., Tetrahedron Lett., 2005, 46, 6453.
