Abstract
An efficient and versatile method for the preparation of a series of perfluoroalkyl containing spiro cyclic barbituric acid derivatives is described. 7,9-Dimethyl-2-(iodomethyl)-3-(perfluoroalkylmethyl) 7,9-diazaspiro[4.5]decane-6,8,10-trione were prepared in good yields from 1,3-dimethylbarbituric acid. The structures of these compounds were confirmed by 1H NMR, 13C NMR, IR, MS spectra and elemental analysis.
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