Abstract
6-Perfluoroalkyl pyrimidine derivatives of well known tyrosine kinase inhibitor imatinib have been synthesised from 1-(pyridin-3-yl)-3-per fluoroalkylbutane-1,3-diones by condensation with a 3 -iodophenylguanidine and then by a Cu(I)-catalysed reaction with a 4-substituted benzamide.
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