Four-Component Reaction of Alkyl Isocyanide,Acetylenic Esters,Phenols and Pyrrole;Synthesis of Dialkyl 2-[(alkylimino)(1H-pyrrol-2-yl)methyl]-3-(aryloxy) Succinate
Free accessResearch articleFirst published online May, 2015
Four-Component Reaction of Alkyl Isocyanide,Acetylenic Esters,Phenols and Pyrrole;Synthesis of Dialkyl 2-[(alkylimino)(1H-pyrrol-2-yl)methyl]-3-(aryloxy) Succinate
A new series of dialkyl 2-[(alkylimino)(1H-pyrrol-2-yl)methyl]-3-(aryloxy)succinate derivatives have been synthesised using alkyl isocyanids, acetylenic esters, phenols with electron-withdrawing groups and pyrrole in CH2Cl2 at ambient temperature.
WalborskyH. M., PersiasamyM. P., The chemistry of functional groups, Supplement C, PataiS., and RappoportZ. eds. Wiley, New York, 1983, Chap. 20, pp. 835–887.
7.
MarcacciniS., and TorrobaT., Org. Prep. Proc. Intl., 1993, 25, 141.