Abstract
An improved method for chemical resolution of DL-phenylalanine methyl ester using N-acetyl-D-phenylglycine as a resolving agent is described. This new resolving agent is readily available, non-toxic and easily recoverable from the insoluble diasteromeric salt. This method was used to obtain D-phenylalanine methyl ester with high optical purity of 98.1% and a high yield of 81.2%.
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