Abstract
An efficient green synthesis of eight 3-amino-12-oxo-1-aryl-1,12-dihydrobenzo[h]pyrano[3,2-c]chromene-2-carbonitriles may be achieved by a three-component, one-pot reaction between 4-hydroxy-2H-benzo[h]chromen-2-one, malononitrile and various araldehydes in water in the presence of NEt3.
References
1.
Domling A.
, and
Ugi I.
, Angew. Chem., Int. Ed. , 2000 , 39 , 3168 .
2.
Kappe C.O.
, Acc. Chem. Res. , 2000 , 33 , 879 .
3.
Rideout D.C.
, and
Breslow R.
, J. Am. Chem. Soc. , 1980 , 102 , 7816 .
4.
Green G.R.
,
Evans J.M.
,
Vong A.K.
(eds), Comprehensive heterocyclic chemistry. Pergamon Press Oxford , 1995 , Vol. 5 , p. 469 .
5.
Foye W.O.
, Principi di chemico farmaceutica , Piccin , Padova, Italy , 1991 , p. 416 .
6.
Singh K.
,
Singh J.
, and
Singh H.
, Tetrahedron , 1996 , 52 , 14273 .
7.
Hatakeyama S.
,
Ochi N.
,
Numata H.
, and
Takano S.A.
, JCS, Chem. Commun. , 1988 , 17 , 1202 .
8.
Shestopalov A.A.
,
Rodinovskaya L.A.
,
Shestopalov A.M.
, and
Litvinov V.P.
, Russ. Chem. Bull. , 2005 , 54 , 992 .
9.
Khurana J.M.
,
Nand B.
, and
Saluja P.
, Tetrahedron , 2010 , 66 , 5637 .
10.
Ge S.Q.
,
Yang X.
,
Wu B.
, and
Xia M.
, Synth. Commun. , 2010 , 40 , 1009 .
11.
Pansuriya A.M.
,
Savant M.M.
,
Bhuva C.V.
,
Singh J.
, and
Naliapava Y.T.
, Arkivoc , 2009 , xii , 254 .
12.
Mirza B.
,
Mirzazadeh R.
, and
Zeeb M.
, J. Chem. Res. , 2013 , 37 , 778 .
