Abstract
A series of novel (1-arylmethyl-3-aryl-1H-pyrazol-5-yl)(4-arylpiperazin-1-yl)methanone derivatives were synthesised. Preliminary study of the structure–activity relationship revealed that 4-chlorophenyl, 4-tert-butylphenyl, 4-fluorophe-nyl and 3-methoxyphenyl had a promising effect on the antifungal activity.
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