Abstract
Several 2, 3-dimethoxy-5-methyl-1, 4-benzoquinones substituted at the C-6 position with alkoxy methyl groups were prepared by a reaction sequence starting from 2, 3, 4, 5-tetramethoxytoluene (alkoxy methyl) via a Blanc chloromethylation reaction, Williamson reaction and oxidation. The method provided a good yield of 2, 3-dimethoxy-5-methyl-1, 4-benzoquinones and is suitable for the synthesis of other benzoquinone analogues.
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