Abstract
The preparation of epoxy steroids derived from testosterone, dehydroisoandrosterone and epiandrosterone using m-chloroperbenzoic acid and their biotransformation by the fungus Mucor plumbeus is described. The results reveal an effect of the epoxide on the biotransformation.
References
1.
Hanson
J.R.
, An introduction to biotransformation in organic Chemistry , W.H. Freeman , San Fancisco, 1998 .
2.
Bensasson
C.M.
,
Hanson
J.R.
, and
Hunter
A.C.
, Phytochemistry , 1998 , 49 , 2355 .
3.
Jones
E.R.H
, Pure Appl. Chem. , 1973 , 33 , 39 .
4.
Holland
H.L.
, Chem. Soc. Reviews. , 1982 , 11 , 371 .
5.
Teske
A.P.
, Microbiology , 2005 , 13 , 402 .
6.
Cambie
R.C.
,
Rutledge
P.S.
,
Scott
D.W.
, and
Woodgate
P.D.
, Austral. J. Chem. , 1979 , 32 , 695 .
7.
Voishvillo
N.E.
,
Turuta
A.M.
, and
Kamernitskii
A.V.
, Russ. Chem. Bull. , 1994 , 43 , 515 .
8.
Hanson
J.R
, and
Yildirim
K.
, J. Chem. Res. (S) , 1999 , 698 .
9.
Hanson
J.R
,
Hitchcock
P.
, and
Hunter
A.C.
, Phytochemistry , 1998 , 49 , 1287 .
