Free accessResearch articleFirst published online 2007-12
A Novel and Efficient Synthesis of Terminal Arylacetylenes via Sonogashira Coupling Reactions Catalysed by MCM-41-supported Bidentate Phosphine Palladium(0) Complex
A variety of terminal arylacetylenes have been conveniently synthesised in good to high yields via Sonogashira coupling of aryl iodides with (trimethylsilyl)acetylene catalysed by a MCM-41-supported bidentate phosphine palladium(0) complex, followed by desilylation. The polymeric palladium catalyst can be reused many times without any decrease in activity.
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