Abstract
The first example of immobilisation of some glycoluril-based molecular clips, which are good receptors for dihydroxybenzenes, on silica gel and alumina is described. 4,4′-Bis(methoxyphenyl)glycoluril was used as the base scaffold for the synthesis of molecular clips. After demethylation of the methoxy groups, the clip compounds were attached to silica gel and alumina using the linker (3-chloropropyl)trimethoxysilane. The resulting clip-functionalised silica gel and alumina could be applied as a stationary phase in an affinity chromatography technique for the separation and purification of dihydroxybenzenes and the more important biologically active catecholamines.
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