Friedel–Crafts acylation of different arenes was carried out in the presence of Cu–Mg (24:76) alloy under microwave irradiation and solvent-free conditions. Different substrates undergo acylation predominantly at the para-position. An efficient, simple, selective Friedel–Crafts acylation reaction affords good yields of the products and the catalyst could be easily recovered and recycled.
HofmannJ.E., and SchriesheimA., Friedel-Crafts and Related Reactions, OlahG.A. (ed.), J. Wiley and Sons, New York, 1964, 2, 597.2.
2.
OlahG.A., Friedel-Crafts Chemistry, J. Wiley & Sons, New York, 1973.
3.
PaulS., NandaP., GuptaR., and LoupyA., Synthesis, 2003, 18, 2877.
4.
SarvariH.M., and SharghiH., J. Org. Chem, 2004, 69, 6953.
5.
(a) LidstromP., TierneyJ., WatheyB., and WestmanJ., Tetrahedron, 2001, 57, 9225; (b) P. Perreux and A. Loupy, Tetrahedron, 2001, 57, 9199.
6.
NagarajaD., and PashaM.A., Tetrahedron Lett, 1999, 40, 7855.
7.
(a) PashaM.A., and JayashankaraV.P., Indian J. Chem2004, 43B, 2464; (b) M.A. Pasha and V.P. Jayashankara, Ultrason. Sonochem., 2006, 13, 42; (c) M.A. Pasha and V.P. Jayashankara, J. Chem. Res (S)., 2004, 4, 282; (d) M.A. Pasha and V.P. Jayashankara, Ultrason. Sonochem., 2005, 12, 433.
8.
PashaM.A., RamachandraswamyN., and JayashankaraV.P., Indian J. Chem.2005, 44B, 823.
