A Clean One-pot Synthesis of 7-Amino-5-Aryl-6-Cyano-1,5-Dihydro-2H-Pyrano[2,3-d] Pyrimidine-2,4(3H)-Diones in Aqueous Media under Ultrasonic Irradiation
Free accessResearch articleFirst published online March, 2005
A Clean One-pot Synthesis of 7-Amino-5-Aryl-6-Cyano-1,5-Dihydro-2H-Pyrano[2,3-d] Pyrimidine-2,4(3H)-Diones in Aqueous Media under Ultrasonic Irradiation
A novel approach to the synthesis of 7-amino-5-aryl-6-cyano-1,5-dihydro-2H-pyrano[2,3-d]pyrimidine-2,4(3H)-diones in aqueous media under ultrasonic irradiation without catalyst is described. This method provides several advantages such as being environmentally friendly, simple work-up procedure and milder condition. In addition, water was chosen as a green solvent.
