The cross-aldol condensations of cyclopentanone, cyclohexanone and acetone with benzaldehyde or cinnamaldehyde were catalysed in the presence of SOCl2, in anhydrous ethanol to synthesise α, α'-bis(substituted benzylidene) ketones with excellent yields(92–97%).
References
1.
MukaiyamaT., BannoK., and NarasakaK., J. Am. Chem. Soc., 1974, 96, 7503.
2.
MahrwaldR., Chem. Rev., 1999, 99, 1095.
3.
IranpoorN., and KazemiF., Tetrahedron, 1998, 54, 9475.
4.
NakanoT., TrifuneS., UmanoS., InadaA., IshiiY., and OgawaM., J. Org. Chem., 1987, 52, 2239.