The enantiomeric hexahydro-10-methylnaphthal-4-en-3-ones are hydroxylated by the fungus, Cephalosporium aphidicola at C-6 and at C-9 (steroid-like enantiomer) or at C-1 (steriod enantiomer).
see KiranI., HansonJ. R., and HunterA. C., J. Chem. Res.2004, 362 and refs therein.
2.
FarooqA., HansonJ. R., and IqbalZ., Phytochemistry, 1994, 37, 723.
3.
HansonJ.R., NasirH., and ParvezA., Phytochemistry, 1996, 42, 411.
4.
see for example, FaberK., Biotransformations in Organic Chemistry, Springer-Verlang, Berlin, 5th edn. 2004.
5.
du FeuE.C., McQuillinF. J., and RobinsonR., J. Chem. Soc., 1937, 53; C. Djerassi and D. Marshal, J. Am. Chem. Soc., 1958, 80, 3986; F. Sondheimer and D. Rosenthal, J. Am. Chem. Soc., 1958, 80, 3995.
6.
HollandH.L., and AuretB. J., Can. J. Chem., 1975, 53, 2041.
