Abstract
o-Nitrophenylazide was reduced by SmI2 in anhydrous THF at room temperature to produce an active intermediate 2 (samarium amide), the ‘living’ double-anion in situ which reacted smoothly with ketones containing active methyl or methylene groups to afford 2,3-dihydro-1H-1,5-benzodiazepines in good yields under mild and neutral conditions.
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