Vitamin B 6 and Erythropoiesis in the Rat. ∗

Abstract

Summary

1) Severe vit. B₆ deficiency in the rat resulted in an increased red cell count and in a reduction in hemoglobin, mean cell volume, and mean cell hemoglobin. The most striking effect was the reduction in mean cell hemoglobin in the deficient rats. The B₆-deficient rats exhibited lymphopenia and granulocytosis. 2) The data show that the rat must be added to the list of animals requiring vit. B₆ for normal hematopoiesis.