Tolerance in Pure Strain Newborn Mice to Tumor Homografts. ∗

Abstract

Summary

Homotransplantation of “Z”(C3H) strain mammary adenocarcinoma to “A”and “Ce”strain mice and “A”strain tumor to “Z”(C3H) strain mice has been accomplished by injecting these tumors within a few hours after birth. After progressive growth in the “A”strain host the “Z”(C3H) tumors retain their histocompatibility characteristics and can be transplanted into adult “Z”(C3H) strain mice but are rejected by adult mice of the “A”strain.