Diet of Adult Female Rats and Relation to Kidney Lesions in Choline Deficient Offspring. ∗

Abstract

Summary

The incidence of hemorrhagic kidneys in young rats after seven days on a diet containing 18% casein, 0.3% added cystine and low in choline is markedly reduced if 0.06 gamma vit. B₁₂/g of food is incorporated in the diet of the mother during the period from birth to weaning. Choline when added at 1 mg/g of food affords very little protection in young males when compared to that shown by 0.06 gamma of vit. B₁₂. This level of added choline (1 mg/g of food) has a greater protective effect in the females.