Abstract
Summary
1. Five mongrel dogs were fed raw horsemeat 3 days and on fourth day, a laparotomy was performed. Samples of venous blood from various segments of gastrointestinal tract were drawn for determinations of ammonia content. The same animals, similarly prepared, were used after an interval of 2 to 3 weeks to test the effect of orally administered antibacterial agents on the level of ammonia in venous blood obtained from various portions of the gastrointestinal tract. For this purpose, neomycin, sulfasuxidine or achromycin were administered preoperatively by mouth for varying periods. 2. The colon was the principal source of ammonia in portal blood. Of three antibacterial substances tested, only neomycin markedly reduced the ammonia content of portal venous blood from the colon.
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