Abstract
Summary
When protein-depleted rats were subjected to 4 days of fasting, the arginase content of the liver increased by 58% while the alkaline phosphatase content decreased by a similar percentage. A simultaneous smaller increment of the rhodanese content was limited to the first 2 days of fasting. The experiments indicate that the initial increase in arginase activity was due to a nonspecific increase in hepatic protein while the later rise was a specific response probably related to the increased protein catabolism.
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